CONTEMPORARY CLINICAL TOOLS FOR ASSESSMENT, DIAGNOSIS AND MANAGEMENT OF ASTHMA

Abstract: Asthma is a chronic heterogeneous inflammatory disorder/syndrome of the airways that affects more than 300 Million people worldwide. Asthma often starts in childhood (Allergic Asthma phenotype).Co morbidities often trigger asthma exacerbations. It’s often difficult to diagnose asthma in young children. Objective tests of lung function aid in the diagnosis of asthma in children > six years of age. Asthma has phenotypes and endotypes.  Biomarkers Ex. Fractional excretion of Nitric Oxide aid in the diagnosis of severe asthma in children and adults. Management of Severe Asthma has undergone a revolution. Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observed in the past 10 years, despite escalating treatment costs.

TREATMENT AND PREVENTION OF ANTHRACYCLINE CARDIOTOXICITY: MOLECULAR DIAGNOSIS OF PRIMARY MEDIASTINAL B CELL LYMPHOMA

Abstract: Primary mediastinal B-cell lymphoma (PMBCL) is a relatively rare lymphoma subtype affecting mainly young adults. Its molecular signature and clinical features resemble classical Hodgkin lymphoma. The optimal chemotherapy for this lymphoma subtype has not been established. The addition of rituximab to anthracycline based chemotherapy improved response rates and survival. Many centers use R-CHOP as standard treatment, but the role of the intensified regimens and consolidation radiotherapy has to be clarified. Recent data coming from retrospective analyses and an ongoing prospective study addressing the problem of consolidation radiotherapy will help to better identify risk groups and apply risk-adapted and effective treatment strategies. The latest research has helped to understand molecular mechanisms of PMBCL pathogenesis and indicated targets of directed therapy for the future. 

ASSESSMENT OF CONVENTIONAL FUNGICIDES AND BIOCHEMICAL EXTRACTS AGAINST TOMATO EARLY BLIGHT DISEASE

Abstract: Fungicidal activity of nine selected conventional fungicides, identified five plant oils and their combined effect against A. solani, the causal pathogen of early blight on tomato. GC-MS analysis of the tested oils indicated that terpene hydrocarbons (97%) with cinnamaldehyde as the major compound; sulfur compounds; fatty acids and organo-sulfurcontaining compounds were the main components in cinnamon, garlic, mustard and onion oils, respectively. In vitro, Speedcide® (difenoconazole) and Cabrioduo® (Dimethomorph + Pyraclostrobin) were the most effective against the A. solani fungus with EC50 values of 94.6 and 88.6 ppm respectively. Toledo® (Tebuconzole) achieved EC50 value of 631.2 ppm. Roxyl-M® was significantly more effective than Roxyl–plus® or Remik®. Speedcide® alone or mixed with mandipropamid or azoxystrobin in Revus-Top® or Cruze® were the lowest effective in vitro. Garlic and mustard oils were more effective in liquid media than solid one. Cinnamon, onion, garlic and bitter almond oils caused moderate fungi-toxicity against early blight pathogen and could be implemented in the IPM program. Lower EC50 values were obtained in case of combinations of fungicides with oils than separate treatments.  Effect of the active conventional fungicides and plant oils on disease indices, relative disease control, chlorophyll content, sugar contents and poly phenol oxidase in tomato plants was also studied. 

THE RESURGENCE OF MILITANCY IN THE NIGERIA’S NIGER DELTA REGION AND ITS DEVASTATING ECONOMIC CONSEQUENCES

Abstract: The Nigeria’s Niger Delta region is the home of oil and gas industry, which accounts for 90 percent of Nigeria’s foreign exchange earnings. But the unbridled exploitation of these natural resources has left the Niger Delta environment and people’s livelihoods devastated. The youths in the region in a bid to draw the attention of the International community to the sorry state of their environmentaround 2003 constituted themselves into militant groups and began attacks on oil producing facilities. These violent acts which heightened in the first instance between 2005 -2009 and again between 2015 – 2016 periods left the Nigerian economy prostrate. Nigerian government’s initial military approaches to containing the crisis in each case only succeeded in its escalation. It was only when government adopted peaceful approaches, first through the granting of amnesty to the militant groups and secondly through the employment of dialogue and continued engagement with the oil bearing communities was relative peace restored in the troubled region. One very important lesson from the Niger Delta crisis is that it’s only through dialogue and continued engagement with the people of the region that permanent peace can be restored in the troubled region.

COMPARATIVE STUDIES ON SOIL SUITABILITY EVALUATION GUIDELINES FOR SELECTED COMMUNITY CROPS IN KHANA LOCAL GOVERNMENT AREA OF RIVERS STATE, SOUTHERN NIGERIA

Abstract A Comparative study on soil suitability evaluation guidelines for selected community crops was carried out in Khana Local Government Area of Rivers State, Southern Nigeria. Eight soil mapping units were recognized and appropriate suitability guidelines specific for each of the community crop of interest were followed in establishing the suitability of the soils of Khana for their cultivation. Various suitability evaluation guidelines of each soil type and each of the different community crops pedon by pedon, were ranked and the rankings were compared using the Spearman’s rho ranking correlation coefficient to ascertain the guidelines that can best accommodate the eight community crops of interest. The results showed that, the suitability guidelines for oil palm correlates with cassava, yam and citrus, while cassava correlates with yam and oil palm and yam correlates with cassava and oil palm. Plantain stands on its own; while the suitability guidelines to be used for maize, fluted pumpkin or okro depends on individual choice as any of the guidelines could be used for their suitability evaluation.

PERSPECTIVES ON INNOVATION AND TECHNOLOGY TRANSFER IMPACT ON THE PERFORMANCE OF WOMEN-OWNED MICRO SMALL MEDIUM ENTERPRISES (MSMES)

Abstract The main objective of the study was to establish the impact of technology transfer on the performance of women-owned MSMEs in Kisii County, Kenya. To achieve this objective a sample size of 288 enterprises was selected based on Israel, G. D.  (1992) sample size formula. A descriptive survey was employed to gather information. Primary data was collected from the indicated target women enterprises using questionnaires. The correlation analysis results revealed that technology transfer had a positive significant association with the performance of women-owned MSMEs in Kisii County, Kenya. The regression analysis results revealed that technology transfer significantly accounted for the positive variability in the performance of women-owned MSMEs in Kisii County, Kenya. The major setback of this study was the exclusive use of questionnaires to collect data. Future studies should consider employing interview guides and secondary information in order to come up with objective reliable findings on the impact of business development services on the performance of women-owned MSMEs. Future studies can also consider determining the moderating effect of the external business environment on the relationship between the business development services and organizational performance in women-owned or youth owned MSMEs.

SYNTHESIS OF EASTERN AND WESTERN CULTURE IN CONTEMPORARY APPROACH: AN ANALYSIS OF RAZA BUKHARI’S CONCEPTUAL PAINTINGS

Abstract:Painting serves as a medium to satisfy artist’s sense of perception and provides space to portray his own imagination. The researcher here reveals an attempt by Raza Bukhari to capture the fusion of two culture’s, western cartoon character fitting in the eastern Persian miniature, or somewhere western subject adorned with Persian motif, creating contemporary approach in the traditional manner of miniature painting, which helps him to produce the visual copy of his expression and display his inner most thoughts. Observing two A tastes on one canvas brings the observer to discover the hidden messages of the visual, to effectuate the need this paper is going to focus the imagery and symbolism used by Raza Bukhari to express the human psychology of adopting foreign culture, and fitting themselves in that. His masterly skills of using opaque colour for creating a painting and the use of cat hair brush, accompanied with other techniques further modifies and helps in delivering the essence of painting.

MOLECULAR INSIGHTS INTO THE GENETIC AND HAPLOTYPE DIVERSITY AMONG FOUR POPULATIONS OF LOCAL ORNAMENTAL PALO FISH (BETTA SP.: OSPHRONEMIDAE)

Abstract: Cytochrome b gene mitochondrial DNA was used to study the Palo fish from Bukit Rangkak tributary, Harau Valley, West Sumatra. The study aimed to determine the taxonomy of Palo fish, which morphological suspected as the Betta group. Phylogenetic analysis was used to solve the relationship of Palo fish with other species of the Betta. The alignment of the DNA sequences was carried out with Clustal X version 2 and analysis of phylogenetic tree using MEGA 6 software program. Based on the analysis of the cytochrome b gene sequence (1047 bp), it is known that the genetic differences of Palo fish from two tributaries of Bukit Rangkak river is 0.0% and with other Betta fish ranges from 13.0-35.5%. The phylogenetic tree has shown that Palo fish has a close genetic relationship with the Betta picta (13.0%). The result showed that Palo fish is at the different species in the genus of Betta and proposed as a new species.

Impact of Customer Feedback Management on Customer Satisfaction in Deposit Money Bank in South-eastern Nigeria

Abstract Impact of customer feedback management on customer satisfaction in deposit money bank in South-eastern Nigeria was examined. The population of the study consists of customers of Access Bank, Ecobank, First Bank and UBA in Abia, Enugu, Awka and Owerri regional offices in South-eastern Nigeria. The target population includes intercepted student customers (undergraduates and post graduates) of those banks. Survey method was adopted for the study and the sample size of 384 was determined using Cochran’s formula. Cronbach’s alpha was used to determine the reliability of the instrument which gave the value of 0.886. Questionnaire was adopted as the instrument for the collection of primary data and was distributed to the 384 students who correctly filled and returned 318. Analysis of data was conducted using simple linear regression analytical technique with the aid of SPSS software version 22. The study revealed that customer feedback management has a significant positive impact on customer satisfaction in deposit money banks in South-eastern Nigeria. Thus, customer feedback management is an effective strategy for achieving customer satisfaction in the Nigerian banking industry. The researchers recommend that Access Bank Plc, Ecobank Plc, First Bank Plc and UBA Plc should continuously improve on managing customer feedback channels to make their customers more satisfied and thus, achieve higher profitability for their shareholders

EFFECT OF RETAINED EARNINGS ON OPERATIONAL PERFORMANCE INDICATORS OF OIL AND GAS FIRMS IN NIGERIA

Abstract: This study appraised the effect of retained earnings on the operational performances of oil and gas firms in Nigeria. The study adopted the Simple Linear regression was adopted in analyzing the secondary data sourced from the financial statements and annual reports of the selected oil companies. Retained earnings are the variable that measured the independent variable while operational performance (dependent variable) was represented using Return on Asset (ROA) and Return on Equity (ROE). The study spanned a ten (10) year period, 2009- 2018. Four (4) oil companies quoted in Nigeria Stock Exchange were used as sample for the study.  The study showed that retained earnings had positive and insignificant effect on both the Return on Asset and Return on Equity of oil and gas firms in Nigeria. This effect was however insignificant for all the sampled oil and gas firms with the exception of Mobil Nigeria Plc in which the retained earnings have a positive and significant effect on the Return on Equity. The paper therefore recommend that the retained earnings of firms in oil and gas companies should be enhanced to impact significantly on the values on the shareholders ROA and ROE.